 | Detroit Lions | | |
| Date |
Opponent |
Time (ET) / Results |
TV |
Location |
| Sun. Sep 13 | @ New Orleans | 1:00 PM | FOX | Superdome |
| Sun. Sep 20 | Minnesota | 1:00 PM | FOX | Ford Field |
| Sun. Sep 27 | Washington | 1:00 PM | FOX | Ford Field |
| Sun. Oct 4 | @ Chicago | 1:00 PM | FOX | Soldier Field |
| Sun. Oct 11 | Pittsburgh | 1:00 PM | CBS | Ford Field |
| Sun. Oct 18 | @ Green Bay | 1:00 PM | FOX | Lambeau Field |
| Sun. Nov 1 | St. Louis | 1:00 PM | FOX | Ford Field |
| Sun. Nov 8 | @ Seattle | 4:05 PM | FOX | Qwest Field |
| Sun. Nov 15 | @ Minnesota | 1:00 PM | FOX | Metrodome |
| Sun. Nov 22 | Cleveland | 1:00 PM | CBS | Ford Field |
| Thu. Nov 26 | Green Bay | 12:30 PM | FOX | Ford Field |
| Sun. Dec 6 | @ Cincinnati | 1:00 PM | FOX | Paul Brown Stadium |
| Sun. Dec 13 | @ Baltimore | 1:00 PM | FOX | M&T Bank Stadium |
| Sun. Dec 20 | Arizona | 1:00 PM | FOX | Ford Field |
| Sun. Dec 27 | @ San Francisco | 4:05 PM | FOX | Candlestick Park |
| Sun. Jan 3 | Chicago | 1:00 PM | FOX | Ford Field |
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