 | San Diego Chargers | | |
| Date |
Opponent |
Time (ET) / Results |
TV |
Location |
| Sun. Sep 7 | Carolina | L 24-26 | FOX | Qualcomm Stadium |
| Sun. Sep 14 | @ Denver | 4:15 PM | CBS | Invesco Field |
| Mon. Sep 22 | New York | 8:30 PM | ESP | Qualcomm Stadium |
| Sun. Sep 28 | @ Oakland | 4:05 PM | CBS | McAfee Coliseum |
| Sun. Oct 5 | @ Miami | 1:00 PM | CBS | Dolphin Stadium |
| Sun. Oct 12 | New England | 8:15 PM | NBC | Qualcomm Stadium |
| Sun. Oct 19 | @ Buffalo | 1:00 PM | CBS | Ralph Wilson Stadium |
| Sun. Oct 26 | @ New Orleans | 1:00 PM | CBS | Wembley Stadium |
| Sun. Nov 9 | Kansas City | 4:15 PM | CBS | Qualcomm Stadium |
| Sun. Nov 16 | @ Pittsburgh | 4:15 PM | CBS | Heinz Field |
| Sun. Nov 23 | Indianapolis | 8:15 PM | NBC | Qualcomm Stadium |
| Sun. Nov 30 | Atlanta | 4:05 PM | FOX | Qualcomm Stadium |
| Thu. Dec 4 | Oakland | 8:15 PM | NFL | Qualcomm Stadium |
| Sun. Dec 14 | @ Kansas City | 1:00 PM | CBS | Arrowhead Stadium |
| Sun. Dec 21 | @ Tampa Bay | 8:15 PM | NBC | Raymond James Stadium |
| Sun. Dec 28 | Denver | 4:15 PM | CBS | Qualcomm Stadium |
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