 | St. Louis Rams | | |
| Date |
Opponent |
Time (ET) / Results |
TV |
Location |
| Sun. Sep 13 | @ Seattle | 4:15 PM | FOX | Qwest Field |
| Sun. Sep 20 | @ Washington | 1:00 PM | FOX | FedEX Field |
| Sun. Sep 27 | Green Bay | 1:00 PM | FOX | Edward Jones Dome |
| Sun. Oct 4 | @ San Francisco | 4:15 PM | FOX | Candlestick Park |
| Sun. Oct 11 | Minnesota | 1:00 PM | FOX | Edward Jones Dome |
| Sun. Oct 18 | @ Jacksonville | 1:00 PM | FOX | Jacksonville Stadium |
| Sun. Oct 25 | Indianapolis | 1:00 PM | CBS | Edward Jones Dome |
| Sun. Nov 1 | @ Detroit | 1:00 PM | FOX | Ford Field |
| Sun. Nov 15 | New Orleans | 1:00 PM | FOX | Edward Jones Dome |
| Sun. Nov 22 | Arizona | 4:05 PM | FOX | Edward Jones Dome |
| Sun. Nov 29 | Seattle | 1:00 PM | FOX | Edward Jones Dome |
| Sun. Dec 6 | @ Chicago | 1:00 PM | FOX | Soldier Field |
| Sun. Dec 13 | @ Tennessee | 1:00 PM | FOX | LP Field |
| Sun. Dec 20 | Houston | 1:00 PM | CBS | Edward Jones Dome |
| Sun. Dec 27 | @ Arizona | 4:05 PM | FOX | U of Phoenix Stadium |
| Sun. Jan 3 | San Francisco | 1:00 PM | FOX | Edward Jones Dome |
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